We recently completed a Phase 2 Expanded Access study to treat serious skin and soft tissue infections. To qualify for this study, patient had to have already tried standard IV therapy without success. The results of this study were promising.
We are currently developing a comparative randomized study where we will compare IV drug delivery to Ultrasonic Drug Dispersion (UDD). Prior to this study, other than topical applications, antibiotics have always been given systemically either orally, intramuscularly (IM) or intravenously (IV). Sometimes an antibiotic must be given systemically because that is the only method to access the infection, for example, with pneumonia, meningitis, or a kidney infection. However, if the infection is located in soft tissue that is readily accessible, then direct delivery of antibiotics becomes an option worth exploring. Since this method does not depend on blood supply to reach the target area, it may be especially advantageous to those with impaired circulation such as diabetic patients.