Barry N. Silberg, M.D., F.A.C.S., Founder, Chief Executive Officer
Dr. Silberg is a board certified Plastic and Reconstructive surgeon and has been in practice in Santa Rosa, CA for 35 years. He is a member of the trauma team at the local level-2 trauma center. After attending Texas A&M University, Dr. Silberg attended The University of Texas Southwestern Medical School in Dallas, Texas. During that time he did research in the Department of Internal Medicine and presented his work at a national meeting. After graduating in 1967, Dr. Silberg completed his internship at The University of Wisconsin followed by serving in the Army in Europe for three years where he earned the Army Commendation Medal. After discharge, he joined the staff of the spinal cord injury service at the Houston Veterans Administration Hospital. He trained in General Surgery under Dr. Michael DeBakey at The Baylor College of Medicine in Houston, Texas and finished his Plastic Surgery training as the first chief resident in Plastic Surgery at The University of California, Davis. He maintained his connection as an instructor in Plastic Surgery as time permitted after completing his training. Dr. Silberg holds several patents and has developed several devices and techniques that aid in Surgery and Plastic Surgery. He has published several papers in peer-reviewed journals and has been a faculty member at international meetings. The current device and technique grew from his investigation into the causes of surgical site infections and wounds that do not heal.
Seth J. Putterman, Ph.D., Chief Technology Officer
Seth Putterman is Professor of Physics at the University of California, Los Angeles. He is a leading researcher in physical acoustics. His discoveries in ultrasonic cavitation, triboelectric x-ray sources, and crystal fusion, have led to a number of high profile news stories. He received a BS from Caltech and a PhD from the Rockefeller University. He is a fellow of the Acoustical Society of America and a Fellow of the American Physical Society. He served on the Board of Parametric Sound [NASDAQ PAMT] and is currently Chair of the Science Advisory Committee of Tribogenics. He is President and CEO of the Julian Schwinger Foundation for Physics Research, and has served for 8 years on the Defense Sciences Research Council. Seth Putterman was named the UCLA 2010–2011 Faculty Research Lecturer. Nature profiled his out-of-the-mainstream approach to science in their October 2005 issue.
David P. Nicolau, PharmD, FCCP, FIDSA, Advisor
Dr. David Nicolau is the Director of the Center for Anti-Infective Research and Development at Hartford Hospital in Hartford, Connecticut. After graduating from Northeastern University, he completed a residency in hospital pharmacy at Boston University Medical Center. After receiving his PharmD from the Medical University of South Carolina, Dr. Nicolau completed a residency in adult internal medicine at the university’s affiliated hospital and a fellowship in Infectious Diseases at Hartford Hospital. Dr. Nicolau’s research activities involve a wide range of preclinical drug development studies to assess the in vitro potency, in vivo efficacy and toxicity profiles of novel compounds. He has been a principal investigator for Phase I – IV studies, as well as Investigational New Drug applications. Dr Nicolau is also widely recognized for his efforts focusing on the development of antimicrobial utilization strategies to improve outcomes and reduce the cost of care in the infected patient and his investigations have been reported in over 560 publications, 400 abstracts and 1,000 local, national or international presentations.
Darrell Zoromski, Board Member, Advisor
Darrell Zoromski is currently a board member on several private medical device and not-for-profit companies. Prior to that, he was CEO of Miramar Labs, a dermatology focused medical device start-up from the Foundry Incubator in Silicon Valley. He and his team received FDA approval, achieved >90% clinical efficacy, raised $35M, and launched commercially generating $10M revenue year 1. Mr. Zoromski has a unique blend of medical device and consumer products experience where he has led and grown businesses ranging in revenues from $100M to $500M over the past 25+ years. His focus has been on driving growth through both product innovation and M&A. Prior to his BOD and Miramar Labs roles, he served as: VP Global Marketing & CMO at Align Technology (Invisalign), General Manager of Optical Laboratories at Carl Zeiss Vision, Director of Breakfast Foods at General Mills, Director of Home Care, Insect Control and Glade Air Care Divisions at S.C. Johnson & Son, and brand management roles in Personal Care at Procter & Gamble. Mr. Zoromski received his Masters in Management with honors from the Kellogg Graduate School of Management at Northwestern University, and his B.A. with honors from the University of Wisconsin, Madison with degrees in Finance, International Business and Marketing.
C. Michele Brule’, Co-Founder, Board Member
Michele Brulé worked in information technology for 16 years before co-founding the Santa Rosa Antibiotic Effectiveness Project in 2007 with Barry N. Silberg, M.D., F.A.C.S. Established as a 501(c)(3), the Project has supported research for treatment of skin and soft tissue infections and chronic wounds. Michele managed the cross-functional business operations of Sonescence until January of 2019 and served as the company’s chief liaison with investors, regulatory agencies, hospital administrators and other professional organizations. She played an integral role is acquiring approval for the Phase 2 expanded access study and managed the entire research team that completed the first cohort. She has also played a primary role in initiating a Phase 2 randomized clinical trial, which is planned to commence within the next six months. Michele was also Business Manager for Dr. Silberg’s Plastic and Reconstructive Surgery facility for 10 years. She was previously part of a team at iCore Technologies, Inc., a start-up company specializing in computer hardware development. She assisted in the acquisition of an SBIR contract with the Department of Defense, as well as managing various aspects of the business. In addition, Michele has served on the Board of Directors of several non-profit agencies. She earned a Master’s Degree in Business Administration, as well as a Bachelor’s Degree in Economics and Business Administration from California State University (Sonoma State University).